Human VAPB protein (Recombinant) (C-His) (STJP014306)

Name: Human VAPB protein (Recombinant) (C-His) (STJP014306)
SKU: STJP014306-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP014306-100

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Short Description	Recombinant-Human VAPB-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 100mM NaCl, pH 8.0.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. Interacts with STARD3 in a FFAT motif phosphorylation dependent manner. Via interaction with WDR44 participates in neosynthesized protein export. Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
Protein Name	Vesicle-Associated Membrane Protein-Associated Protein B/C Vamp-B/Vamp-C Vamp-Associated Protein B/C Vap-B/Vap-C
Database Links	Reactome: R-HSA-1660661 Reactome: R-HSA-8980692 Reactome: R-HSA-9013106 Reactome: R-HSA-9013404 Reactome: R-HSA-9013405 Reactome: R-HSA-9013408
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Type Iv Membrane Protein Present In Mitochondria-Associated Membranes That Are Endoplasmic Reticulum Membrane Regions Closely Apposed To The Outer Mitochondrial Membrane
Alternative Protein Names	Vesicle-Associated Membrane Protein-Associated Protein B/C protein Vamp-B/Vamp-C protein Vamp-Associated Protein B/C protein Vap-B/Vap-C protein VAPB protein UNQ484 protein PRO983 protein

Information sourced from Uniprot.org