| Short Description : | Recombinant-Human VAMP-4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | VAMP4 |
| Gene ID: | 8674 |
| Uniprot ID: | VAMP4_HUMAN |
| Accession Number: | NP_003753 |
| Immunogen: | Human |
| Immunogen Region: | 1-115aa |
| Immunogen Sequence: | MPPKFKRHLN DDDVTGSVKS ERRNLLEDDS DEEEDFFLRG PSGPRFGPRN DKIKHVQNQV DEVIDVMQEN ITKVIERGER LDELQDKSES LSDNATAFSN RSKQLRRQMW WRGCKLEHHH HHH |
| Function | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. |
| Protein Name | Vesicle-Associated Membrane Protein 4Vamp-4 |
| Database Links | Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Iv Membrane ProteinAssociated With Trans Golgi Network (Tgn) And Newly Formed Immature Secretory Granules (Isg)Not Found On The Mature Secretory Organelles |
| Alternative Protein Names | Vesicle-Associated Membrane Protein 4 proteinVamp-4 proteinVAMP4 protein |
Information sourced from Uniprot.org
