Human VAChT (Vesicular Acetylcholine Transporter) Sandwich ELISA Kit (STJE0012964)
SPECIFICATIONS
General Information
| Short Description | This VAChT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.117ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | SLC18A3 |
| Gene ID | 6572 |
| Uniprot ID | VACHT_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Peripheral and central cholinergic nervous systems. |
| Post Translational Modifications | |
| Function | Electrogenic antiporter that exchanges one cholinergic neurotransmitter, acetylcholine or choline, with two intravesicular protons across the membrane of synaptic vesicles. Uses the electrochemical proton gradient established by the V-type proton-pump ATPase to store neurotransmitters inside the vesicles prior to their release via exocytosis. Determines cholinergic vesicular quantal size at presynaptic nerve terminals in developing neuro-muscular junctions with an impact on motor neuron differentiation and innervation pattern. Part of forebrain cholinergic system, regulates hippocampal synapse transmissions that underlie spatial memory formation. Can transport serotonin. |
| Protein Name | Vesicular Acetylcholine TransporterVachtSolute Carrier Family 18 Member 3 |
| Database Links | Reactome: R-HSA-264642Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Vesicular Acetylcholine Transporter ELISA kitVacht ELISA kitSolute Carrier Family 18 Member 3 ELISA kitSLC18A3 ELISA kitVACHT ELISA kit |
| output |
Information sourced from Uniprot.org