• Human uPAR/PLAUR/CD87 protein (Recombinant) (C-His) (STJP001063)
  • Human uPAR/PLAUR/CD87 protein (Recombinant) (C-His) (STJP001063)
  • Human uPAR/PLAUR/CD87 protein (Recombinant) (C-His) (STJP001063)
  • Human uPAR/PLAUR/CD87 protein (Recombinant) (C-His) (STJP001063)

Human uPAR/PLAUR/CD87 protein (Recombinant) (C-His) (STJP001063)

SKU:
STJP001063

£76.50 - £248.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human uPAR/PLAUR/CD87-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human PLAUR at 1 Mu g/mL (100 Mu L/well) can bind PLAUR Rabbit pAb with a linear range of 0.03-14.17ng/mL.
Gene Symbol: PLAUR
Gene ID: 5329
Uniprot ID: UPAR_HUMAN
Immunogen: Recombinant Human uPAR/PLAUR/CD87 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu23-Arg303) of human uPAR (Accession #NP_002650.1) fused with a 6×His tag at the C-terminus.
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Protein Names Urokinase Plasminogen Activator Surface Receptor protein
U-Par protein
Upar protein
Monocyte Activation Antigen Mo3 protein
Cd Antigen Cd87 protein
PLAUR protein
MO3 protein
UPAR protein

Information sourced from Uniprot.org

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