Human UNC119B protein (Recombinant) (His-Tag) (STJP017521)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human UNC119B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 100mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UNC119B |
| Gene ID | 84747 |
| Uniprot ID | U119B_HUMAN |
| Accession Number | NP_001074002 |
| Immunogen | Human |
| Immunogen Region | 1-251aa |
| Immunogen Sequence |
Additional Info
| Function | Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells. |
| Protein Name | Protein Unc-119 Homolog B |
| Database Links | Reactome: R-HSA-5624138 |
| Cellular Localisation | Cell ProjectionCiliumEnriched At The Transition Zone And Extended Into The Proximal End Of The Cilium |
| Alternative Protein Names | Protein Unc-119 Homolog B proteinUNC119B protein |
Information sourced from Uniprot.org