Human Ufc1 protein (Recombinant) (His-Tag) (STJP017198)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017198
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General Information

Short DescriptionRecombinant-Human Ufc1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolUFC1
Gene ID51506
Uniprot IDUFC1_HUMAN
Accession NumberNP_057490
ImmunogenHuman
Immunogen Region1-167aa
Immunogen Sequence MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD NDWFRLESNK EGTRWFGKCW YIHDLLKYEF DIEFDIPITY PTTAPEIAVP ELDGKTAKMY RGGKICLTDH FKPLWARNVP KFGLAHLMAL GLGPWLAVEI PDLIQKGVIQ HKEKCNQ

Additional Info

Post Translational Modifications Ufmylated at Lys-122. Deufmylated by UFSP1.
Function E2-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy).
Protein Name Ubiquitin-Fold Modifier-Conjugating Enzyme 1
Ufm1-Conjugating Enzyme 1
Database Links
Cellular Localisation
Alternative Protein Names Ubiquitin-Fold Modifier-Conjugating Enzyme 1 protein
Ufm1-Conjugating Enzyme 1 protein
UFC1 protein
CGI-126 protein
HSPC155 protein

Information sourced from Uniprot.org

Citations

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