Human UBL5 protein (Recombinant) (His-Tag) (STJP017217)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human UBL5-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBL5 |
| Gene ID | 59286 |
| Uniprot ID | UBL5_HUMAN |
| Accession Number | NP_077268 |
| Immunogen | Human |
| Immunogen Region | 1-73aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and lymphoblasts. |
| Function | Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins. Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers. Also plays a protective role against ER stress-induced apoptosis. |
| Protein Name | Ubiquitin-Like Protein 5 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusCajal Body |
| Alternative Protein Names | Ubiquitin-Like Protein 5 proteinUBL5 protein |
Information sourced from Uniprot.org