Human UBE2V2 protein (Recombinant) (N-His) (STJP014642)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human UBE2V2-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 50mm HEPES, 150mM NaCl, pH 7.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | UBE2V2 |
| Gene ID | 7336 |
| Uniprot ID | UB2V2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Asn145 |
Additional Info
| Function | Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 Variant 2Ddvit 1Enterocyte Differentiation-Associated Factor 1Edaf-1Enterocyte Differentiation-Promoting Factor 1Edpf-1Mms2 HomologVitamin D3-Inducible Protein |
| Database Links | Reactome: R-HSA-5693565Reactome: R-HSA-5693571Reactome: R-HSA-5693607Reactome: R-HSA-5696395Reactome: R-HSA-69473Reactome: R-HSA-8866654Reactome: R-HSA-983168 |
| Cellular Localisation | |
| Alternative Protein Names | Ubiquitin-Conjugating Enzyme E2 Variant 2 proteinDdvit 1 proteinEnterocyte Differentiation-Associated Factor 1 proteinEdaf-1 proteinEnterocyte Differentiation-Promoting Factor 1 proteinEdpf-1 proteinMms2 Homolog proteinVitamin D3-Inducible Protein proteinUBE2V2 proteinMMS2 proteinUEV2 protein |
Information sourced from Uniprot.org