Human UbcH8/UBE2L6 protein (Recombinant) (His-Tag) (STJP019797)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human UbcH8/UBE2L6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1mM PMSF, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE2L6 |
| Gene ID | 9246 |
| Uniprot ID | UB2L6_HUMAN |
| Accession Number | NP_004214 |
| Immunogen | Human |
| Immunogen Region | 1-152aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Present in natural killer cells (at protein level). |
| Post Translational Modifications | ISGylated. |
| Function | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. |
| Protein Name | Ubiquitin/Isg15-Conjugating Enzyme E2 L6E2 Ubiquitin-Conjugating Enzyme L6Retinoic Acid-Induced Gene B ProteinRig-BUbch8Ubiquitin Carrier Protein L6Ubiquitin-Protein Ligase L6 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-168928Reactome: R-HSA-5656169Reactome: R-HSA-936440Reactome: R-HSA-977225Reactome: R-HSA-983168Reactome: R-HSA-9833110Reactome: R-HSA-9833482Reactome: R-HSA-9909505 |
| Cellular Localisation | |
| Alternative Protein Names | Ubiquitin/Isg15-Conjugating Enzyme E2 L6 proteinE2 Ubiquitin-Conjugating Enzyme L6 proteinRetinoic Acid-Induced Gene B Protein proteinRig-B proteinUbch8 proteinUbiquitin Carrier Protein L6 proteinUbiquitin-Protein Ligase L6 proteinUBE2L6 proteinUBCH8 protein |
Information sourced from Uniprot.org