Human UBAP1 protein (Recombinant) (C-His) (STJP014742)

SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP014742-100
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General Information

Short DescriptionRecombinant-Human UBAP1-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt.
Endotoxin< 1 EU/ยตg as determined by LAL test.

Target Information

Gene SymbolUBAP1
Gene ID51271
Uniprot IDUBAP1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Ser502

Additional Info

Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.
Protein Name Ubiquitin-Associated Protein 1
Ubap-1
Nasopharyngeal Carcinoma-Associated Gene 20 Protein
Database Links Reactome: R-HSA-162588
Reactome: R-HSA-174490
Reactome: R-HSA-917729
Reactome: R-HSA-9610379
Reactome: R-HSA-9615710
Cellular Localisation Cytoplasm
Cytosol
Endosome
Predominantly Cytosolic
Recruited To Endosomes As Part Of The Escrt-I Complex
Alternative Protein Names Ubiquitin-Associated Protein 1 protein
Ubap-1 protein
Nasopharyngeal Carcinoma-Associated Gene 20 Protein protein
UBAP1 protein
NAG20 protein

Information sourced from Uniprot.org

Citations

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