Human U2AF1 protein (Recombinant) (His-Tag) (STJP018202)

Name: Human U2AF1 protein (Recombinant) (His-Tag) (STJP018202)
SKU: STJP018202
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018202

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Short Description	Recombinant-Human U2AF1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE/Denatured
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	U2AF1
Gene ID	7307
Uniprot ID	U2AF1_HUMAN
Accession Number	NP_001020374
Immunogen	Human
Immunogen Region	1-240aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSMAEYLAS IFGTEKDKVN CSFYFKIGAC RHGDRCSRLH NKPTFSQTIL IQNIYRNPQN SAQTADGSHC AVSDVEMQEH YDEFFEEVFT EMEEKYGEVE EMNVCDNLGD HLVGNVYVKF RREEDAEKAV IDLNNRWFNG QPIHAELSPV TDFREACCRQ YEMGECTRGG FCNFMHLKPI SRELRRELYG RRRKKHRSRS RSRERRSR

Function	Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Protein Name	Splicing Factor U2af 35 Kda Subunit U2 Auxiliary Factor 35 Kda Subunit U2 Small Nuclear Rna Auxiliary Factor 1 U2 Snrnp Auxiliary Factor Small Subunit
Database Links	Reactome: R-HSA-159236 Reactome: R-HSA-72163 Reactome: R-HSA-72187 Reactome: R-HSA-73856
Cellular Localisation	Nucleus Nucleus Speckle
Alternative Protein Names	Splicing Factor U2af 35 Kda Subunit protein U2 Auxiliary Factor 35 Kda Subunit protein U2 Small Nuclear Rna Auxiliary Factor 1 protein U2 Snrnp Auxiliary Factor Small Subunit protein U2AF1 protein U2AF35 protein U2AFBP protein FP793 protein

Information sourced from Uniprot.org