Human TYW5 protein (Recombinant) (His-Tag) (STJP017958)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human TYW5-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TYW5 |
| Gene ID | 129450 |
| Uniprot ID | TYW5_HUMAN |
| Accession Number | NP_001034782 |
| Immunogen | Human |
| Immunogen Region | 1-315aa |
| Immunogen Sequence |
Additional Info
| Function | tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes. |
| Protein Name | Trna Wybutosine-Synthesizing Protein 5Htyw5Trna Yw-Synthesizing Protein 5Trna(Phe7-(3-Amino-3-Carboxypropylwyosine(37-C(2-Hydroxylase |
| Database Links | Reactome: R-HSA-6782861 |
| Cellular Localisation | |
| Alternative Protein Names | Trna Wybutosine-Synthesizing Protein 5 proteinHtyw5 proteinTrna Yw-Synthesizing Protein 5 proteinTrna(Phe protein7-(3-Amino-3-Carboxypropylwyosine(37-C(2-Hydroxylase proteinTYW5 proteinC2orf60 protein |
Information sourced from Uniprot.org