Human TTYH3 protein (Recombinant) (C-His) (STJP014764)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TTYH3-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | TTYH3 |
| Gene ID | 80727 |
| Uniprot ID | TTYH3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | [Asn108-Leu211] & [Gly258-Glu386] |
Additional Info
| Post Translational Modifications | Ubiquitinated by NEDD4L. N-Glycosylated. Contains high-mannose, hybrid and complex oligosaccharides. |
| Function | Calcium-independent, swelling-dependent volume-regulated anion channel (VRAC-swell) which plays a pivotal role in the process of regulatory volume decrease (RVD) in the brain through the efflux of anions like chloride and organic osmolytes like glutamate. Probable large-conductance Ca(2+)-activated chloride channel. |
| Protein Name | Protein Tweety Homolog 3Htty3Volume-Regulated Anion Channel Subunit Ttyh3 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Protein Tweety Homolog 3 proteinHtty3 proteinVolume-Regulated Anion Channel Subunit Ttyh3 proteinTTYH3 proteinKIAA1691 protein |
Information sourced from Uniprot.org