Human TSPAN15 protein (Recombinant) (N-His) (STJP010799)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TSPAN15-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TSPAN15 |
| Gene ID | 23555 |
| Uniprot ID | TSN15_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr115-Ala235 |
Additional Info
| Function | Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity. |
| Protein Name | Tetraspanin-15Tspan-15Tetraspan Net-7Transmembrane 4 Superfamily Member 15 |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLate Endosome Membrane |
| Alternative Protein Names | Tetraspanin-15 proteinTspan-15 proteinTetraspan Net-7 proteinTransmembrane 4 Superfamily Member 15 proteinTSPAN15 proteinNET7 proteinTM4SF15 proteinUNQ677 proteinPRO1311 protein |
Information sourced from Uniprot.org