Human TSPAN1 (Tetraspanin 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019233)

Name: Human TSPAN1 (Tetraspanin 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019233)
SKU: STJE0019233
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

STJE0019233

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Short Description	This TSPAN1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Applications	ELISA
Reactivity	Human
Sensitivity	0.074ng/mL
Detection Limit	0.156-10ng/mL
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Storage Instruction	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time	3 hrs

Gene Symbol	TSPAN1
Gene ID	10103
Uniprot ID	TSN1_HUMAN
Immunogen Region	Ready-To-Use
Sample Type	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Regulates neuronal differentiation in response to NGF by facilitating NGF-mediated activation of NTRK1/TRKA receptor tyrosine kinase and subsequent downstream signaling pathways. Plays a role in the inhibition of TNFalpha-induced apoptosis. Mechanistically, inhibits the NF-kappa-B signaling pathway by blocking phosphorylation of CHUK. Also promotes the stability of the thiamine transporter 1/SLC19A2 in intestinal epithelial cells leading to an increase of thiamine uptake process.
Protein Name	Tetraspanin-1 Tspan-1 Tetraspan Net-1 Tetraspanin Tm4-C
Database Links
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Lysosome Membrane
Alternative ELISA Names	Tetraspanin-1 ELISA kit Tspan-1 ELISA kit Tetraspan Net-1 ELISA kit Tetraspanin Tm4-C ELISA kit TSPAN1 ELISA kit
output

Information sourced from Uniprot.org