Human TRPV3 protein (Recombinant) (N-His) (STJP005722)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TRPV3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TRPV3 |
| Gene ID | 162514 |
| Uniprot ID | TRPV3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn671-Val790 |
Additional Info
| Function | Non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. The channel pore can dilate to provide permeability to larger cations. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen). |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily V Member 3Trpv3Vanilloid Receptor-Like 3Vrl-3 |
| Database Links | Reactome: R-HSA-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmLysosomeTargeted To Lysosome For Degradation In A Snx11-Dependent Manner |
| Alternative Protein Names | Transient Receptor Potential Cation Channel Subfamily V Member 3 proteinTrpv3 proteinVanilloid Receptor-Like 3 proteinVrl-3 proteinTRPV3 protein |
Information sourced from Uniprot.org