Human TRPC6 protein (Recombinant) (N-His) (STJP006227)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TRPC6-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TRPC6 |
| Gene ID | 7225 |
| Uniprot ID | TRPC6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu192 |
Additional Info
| Post Translational Modifications | Phosphorylated by FYN, leading to an increase of TRPC6 channel activity. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 6Trpc6Transient Receptor Protein 6Trp-6 |
| Database Links | Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Short Transient Receptor Potential Channel 6 proteinTrpc6 proteinTransient Receptor Protein 6 proteinTrp-6 proteinTRPC6 proteinTRP6 protein |
Information sourced from Uniprot.org