Human Troponin I1/TNNI1 protein (Recombinant) (His-Tag) (STJP017899)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Troponin I1/TNNI1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNNI1 |
| Gene ID | 7135 |
| Uniprot ID | TNNI1_HUMAN |
| Accession Number | NP_003272.3 |
| Immunogen | Human |
| Immunogen Region | 1-187aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. |
| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Protein Name | Troponin I - Slow Skeletal MuscleTroponin I - Slow-Twitch Isoform |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Protein Names | Troponin I - Slow Skeletal Muscle proteinTroponin I - Slow-Twitch Isoform proteinTNNI1 protein |
Information sourced from Uniprot.org