Human TRIAP1 protein (Recombinant) (His-Tag) (STJP018531)

Name: Human TRIAP1 protein (Recombinant) (His-Tag) (STJP018531)
SKU: STJP018531
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018531

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Short Description	Recombinant-Human TRIAP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	TRIAP1
Gene ID	51499
Uniprot ID	TRIA1_HUMAN
Accession Number	NP_057483
Immunogen	Human
Immunogen Region	1-76aa
Immunogen Sequence	MNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS

Function	Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
Protein Name	Tp53-Regulated Inhibitor Of Apoptosis 1 Protein 15e1.1 Wf-1 P53-Inducible Cell-Survival Factor P53csv
Database Links	Reactome: R-HSA-6803204 Reactome: R-HSA-9837999
Cellular Localisation	Mitochondrion Mitochondrion Intermembrane Space
Alternative Protein Names	Tp53-Regulated Inhibitor Of Apoptosis 1 protein Protein 15e1.1 protein Wf-1 protein P53-Inducible Cell-Survival Factor protein P53csv protein TRIAP1 protein 15E1.1 protein HSPC132 protein

Information sourced from Uniprot.org