Human TPP1 protein (Recombinant) (N-His) (STJP003195)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TPP1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TPP1 |
| Gene ID | 1200 |
| Uniprot ID | TPP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Val320 |
Additional Info
| Post Translational Modifications | Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity. |
| Function | Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus. |
| Protein Name | Tripeptidyl-Peptidase 1Tpp-1Cell Growth-Inhibiting Gene 1 ProteinLysosomal Pepstatin-Insensitive ProteaseLpicTripeptidyl AminopeptidaseTripeptidyl-Peptidase ITpp-I |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | LysosomeMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Tripeptidyl-Peptidase 1 proteinTpp-1 proteinCell Growth-Inhibiting Gene 1 Protein proteinLysosomal Pepstatin-Insensitive Protease proteinLpic proteinTripeptidyl Aminopeptidase proteinTripeptidyl-Peptidase I proteinTpp-I proteinTPP1 proteinCLN2 proteinGIG1 proteinUNQ267 proteinPRO304 protein |
Information sourced from Uniprot.org