Human TPM3 protein (Recombinant) (His-Tag) (STJP017491)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017491
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General Information

Short DescriptionRecombinant-Human TPM3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol, 0.1M NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTPM3
Gene ID7170
Uniprot IDTPM3_HUMAN
Accession NumberNP_705935.1
ImmunogenHuman
Immunogen Region1-248aa
Immunogen SequenceMAGITT IEAVKRKIQV LQQQADDAEE RAERLQREVE GERRAREQAE AEVASLNRRI QLVEEELDRA QERLATALQK LEEAEKAADE SERGMKVIEN RALKDEEKME LQEIQLKEAK HIAEEADRKY EEVARKLVII EGDLERTEER AELAESRCRE MDEQIRLMDQ NLKCLSAAEE KYSQKEDKYE EEIKILTDKL KEAETR

Additional Info

Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Protein Name Tropomyosin Alpha-3 Chain
Gamma-Tropomyosin
Tropomyosin-3
Tropomyosin-5
Htm5
Database Links Reactome: R-HSA-390522
Reactome: R-HSA-445355
Reactome: R-HSA-9013424
Reactome: R-HSA-9725370
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative Protein Names Tropomyosin Alpha-3 Chain protein
Gamma-Tropomyosin protein
Tropomyosin-3 protein
Tropomyosin-5 protein
Htm5 protein
TPM3 protein

Information sourced from Uniprot.org

Citations

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