Human tPK1 (Tau-Protein Kinase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019147)
SPECIFICATIONS
General Information
| Short Description | This tPK1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.065ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | TPK1 |
| Gene ID | 27010 |
| Uniprot ID | TPK1_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. |
| Post Translational Modifications | |
| Function | Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence. |
| Protein Name | Thiamine Pyrophosphokinase 1Htpk1Placental Protein 20Pp20Thiamin Pyrophosphokinase 1 |
| Database Links | Reactome: R-HSA-196819 |
| Cellular Localisation | |
| Alternative ELISA Names | Thiamine Pyrophosphokinase 1 ELISA kitHtpk1 ELISA kitPlacental Protein 20 ELISA kitPp20 ELISA kitThiamin Pyrophosphokinase 1 ELISA kitTPK1 ELISA kit |
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Information sourced from Uniprot.org