Human TNFSF13/APRIL/CD256 Trimer protein (Recombinant) (N-His&Flag) (STJP020108)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human MUC16/CA125 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Lys112-Leu250 Trimer) of human APRIL (Accession #O75888) fused with a 6xHis, Flag tag at the N-terminus.
General Information
| Short Description | Recombinant-Human TNFSF13/APRIL/CD256 Trimer-N-His&Flag protein was developed in hek293 cells using the region Lys112-Leu250 Trimer. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | TNFSF13 |
| Gene ID | 8741 |
| Uniprot ID | TNF13_HUMAN |
| Immunogen | Recombinant Human MUC16/CA125 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Lys112-Leu250 Trimer) of human APRIL (Accession #O75888) fused with a 6xHis, Flag tag at the N-terminus. |
| Immunogen Region | Lys112-Leu250 Trimer |
Additional Info
| Tissue Specificity | Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
| Post Translational Modifications | The precursor is cleaved by furin. |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 13A Proliferation-Inducing LigandAprilTnf- And Apol-Related Leukocyte Expressed Ligand 2Tall-2Tnf-Related Death Ligand 1Trdl-1Cd Antigen Cd256 |
| Database Links | Reactome: R-HSA-450520Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 13 proteinA Proliferation-Inducing Ligand proteinApril proteinTnf- And Apol-Related Leukocyte Expressed Ligand 2 proteinTall-2 proteinTnf-Related Death Ligand 1 proteinTrdl-1 proteinCd Antigen Cd256 proteinTNFSF13 proteinAPRIL proteinTALL2 proteinZTNF2 proteinUNQ383 proteinPRO715 protein |
Information sourced from Uniprot.org