Human TNFRSF10D/DcR2/TRAIL-R4/CD264 protein (Recombinant) (C-hFc & His) (STJP002679)

SKU:
STJP002679

£59.50 - £156.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human TNFRSF10D/DcR2/TRAIL-R4/CD264-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: 1.Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human TRAIL at 2 Mu g/mL (100 Mu L/well) can bind Recombinant Human DcR2 with a linear range of 15-60 ng/mL.2.Measured by its ability to inhibit TRAIL-mediated cytotoxic
Gene Symbol: TNFRSF10D
Gene ID: 8793
Uniprot ID: TR10D_HUMAN
Immunogen Region: Ala 56-His 211
Immunogen: Active Recombinant Human TNFRSF10D/DcR2/TRAIL-R4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala 56-His 211) of human DcR2 (Accession #NP_003831.2) fused with an Fc, 6×His tag at the C-terminu
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. it cannot but it can induce the NF-kappa-B pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 10d
Decoy Receptor 2
Dcr2
Tnf-Related Apoptosis-Inducing Ligand Receptor 4
Trail Receptor 4
Trail-R4
Trail Receptor With A Truncated Death Domain
Cd Antigen Cd264
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6803211
Reactome: R-HSA-75158
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 10d protein
Decoy Receptor 2 protein
Dcr2 protein
Tnf-Related Apoptosis-Inducing Ligand Receptor 4 protein
Trail Receptor 4 protein
Trail-R4 protein
Trail Receptor With A Truncated Death Domain protein
Cd Antigen Cd264 protein
TNFRSF10D protein
DCR2 protein
TRAILR4 protein
TRUNDD protein
UNQ251 protein
PRO288 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance