Anti-Recombinant-CD264/TNFRSF10D/TRAIL-R4 antibody [RM2K62] (STJA0025927)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Tumor Necrosis Factor Receptor Superfamily Member 10d for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2K62 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TNFRSF10D |
| Gene ID | 8793 |
| Uniprot ID | TR10D_HUMAN |
Additional Info
| Function | Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. it cannot but it can induce the NF-kappa-B pathway. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 10dDecoy Receptor 2Dcr2Tnf-Related Apoptosis-Inducing Ligand Receptor 4Trail Receptor 4Trail-R4Trail Receptor With A Truncated Death DomainCd Antigen Cd264 |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-6803211Reactome: R-HSA-75158 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 10d antibodyAnti-Decoy Receptor 2 antibodyAnti-Dcr2 antibodyAnti-Tnf-Related Apoptosis-Inducing Ligand Receptor 4 antibodyAnti-Trail Receptor 4 antibodyAnti-Trail-R4 antibodyAnti-Trail Receptor With A Truncated Death Domain antibodyAnti-Cd Antigen Cd264 antibodyAnti-TNFRSF10D antibodyAnti-DCR2 antibodyAnti-TRAILR4 antibodyAnti-TRUNDD antibodyAnti-UNQ251 antibodyAnti-PRO288 antibody |
Information sourced from Uniprot.org