Human TNF beta (TNF beta) Antibody Pair (STJAP00736)
General Information
| Short Description | This TNF beta antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R02-6Q1/R02-5C6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LTA |
| Gene ID | 4049 |
| Uniprot ID | TNFB_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. |
| Protein Name | Lymphotoxin-AlphaLt-AlphaTnf-BetaTumor Necrosis Factor Ligand Superfamily Member 1 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5669034Reactome: R-HSA-5676594 |
| Cellular Localisation | SecretedMembraneThe Homotrimer Is SecretedThe Heterotrimer Is Membrane-Associated |
| Alternative Antibody Pair Names | Lymphotoxin-Alpha antibody pairLt-Alpha antibody pairTnf-Beta antibody pairTumor Necrosis Factor Ligand Superfamily Member 1 antibody pairLTA antibody pairTNFB antibody pairTNFSF1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human TNF beta (TNF beta) Antibody Pair (STJAP00736)
This antibody pair is designed to detect human TNF beta (Lymphotoxin-alpha, UniProt P01374) and has confirmed reactivity with human samples only.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2, and purified by affinity chromatography. Clone IDs are R02-6Q1 and R02-5C6 respectively.
This antibody pair has been validated for use in ELISA. No other assay formats are listed in the product specifications.
Optimal working concentrations for both antibodies are to be determined by the end user and are not specified in the product data. Titration experiments are recommended when setting up the assay.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, they should be aliquoted and kept at -20°C, with repeated freeze/thaw cycles avoided to maintain activity.
Both antibodies in this pair were raised against a recombinant human TNF beta protein. No further details regarding the specific immunogen region are provided in the product specifications.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.