| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human TJP2-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | TJP2 |
| Gene ID: | 9414 |
| Uniprot ID: | ZO2_HUMAN |
| Immunogen Region: | Gly307-Ala669 |
| Immunogen: | Homo sapiens (Human) |
| Function | Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity. |
| Protein Name | Tight Junction Protein 2Tight Junction Protein Zo-2Zona Occludens Protein 2Zonula Occludens Protein 2 |
| Database Links | Reactome: R-HSA-2028269Reactome: R-HSA-351906Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideTight JunctionNucleusAlso Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell CulturesLocalizes To Tight Junctions During Initial Stages Of Their Formation |
| Alternative Protein Names | Tight Junction Protein 2 proteinTight Junction Protein Zo-2 proteinZona Occludens Protein 2 proteinZonula Occludens Protein 2 proteinTJP2 proteinX104 proteinZO2 protein |
Information sourced from Uniprot.org