Human TITF1 (Thyroid Transcription Factor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019002)
SPECIFICATIONS
General Information
| Short Description | This TITF1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.062ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | NKX2-1 |
| Gene ID | 7080 |
| Uniprot ID | NKX21_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Thyroid and lung. |
| Post Translational Modifications | Phosphorylated on serine residues by STK3/MST2. |
| Function | Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1. |
| Protein Name | Homeobox Protein Nkx-2.1Homeobox Protein Nk-2 Homolog AThyroid Nuclear Factor 1Thyroid Transcription Factor 1Ttf-1Thyroid-Specific Enhancer-Binding ProteinT/Ebp |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Homeobox Protein Nkx-2.1 ELISA kitHomeobox Protein Nk-2 Homolog A ELISA kitThyroid Nuclear Factor 1 ELISA kitThyroid Transcription Factor 1 ELISA kitTtf-1 ELISA kitThyroid-Specific Enhancer-Binding Protein ELISA kitT/Ebp ELISA kitNKX2-1 ELISA kitNKX2A ELISA kitTITF1 ELISA kitTTF1 ELISA kit |
| output |
Information sourced from Uniprot.org