Human TIMP2 (TIMP2) Antibody Pair (STJAP00923)
General Information
| Short Description | This TIMP2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R01-1D-5/R09-5T-3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TIMP2 |
| Gene ID | 7077 |
| Uniprot ID | TIMP2_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Post Translational Modifications | The activity of TIMP2 is dependent on the presence of disulfide bonds. |
| Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. |
| Protein Name | Metalloproteinase Inhibitor 2Csc-21kTissue Inhibitor Of Metalloproteinases 2Timp-2 |
| Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695Reactome: R-HSA-9839383 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Metalloproteinase Inhibitor 2 antibody pairCsc-21k antibody pairTissue Inhibitor Of Metalloproteinases 2 antibody pairTimp-2 antibody pairTIMP2 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human TIMP2 (TIMP2) Antibody Pair (STJAP00923)
This antibody pair detects human TIMP2 (Tissue Inhibitor of Metalloproteinases 2), corresponding to UniProt accession P16035. Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonal IgGs. The clone IDs are R01-1D-5 and R09-5T-3, and both were raised against a recombinant protein immunogen.
This antibody pair has been validated for use in ELISA. It is intended for research use only and has not been validated for diagnostic or therapeutic applications.
Both antibodies are unconjugated and supplied in 0.01M PBS at pH 7.2. They have been purified by affinity purification.
Working dilutions are not predefined for this product and should be determined by the end user based on their specific experimental conditions and assay setup.
The antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.