Human TIMM13 protein (Recombinant) (N-His-SUMO) (STJP008275)

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STJP008275
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TIMM13-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TIMM13
Gene ID: 26517
Uniprot ID: TIM13_HUMAN
Immunogen Region: Asp18-Met95
Immunogen: Homo sapiens (Human)
Function Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Protein Name Mitochondrial Import Inner Membrane Translocase Subunit Tim13
Database Links Reactome: R-HSA-1268020
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Intermembrane Side
Alternative Protein Names Mitochondrial Import Inner Membrane Translocase Subunit Tim13 protein
TIMM13 protein
TIM13B protein
TIMM13A protein
TIMM13B protein

Information sourced from Uniprot.org