Human Thymidylate synthase/TYMS protein (Recombinant) (His-Tag) (STJP016588)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Thymidylate synthase/TYMS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.1 M NaCl. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TYMS |
| Gene ID | 7298 |
| Uniprot ID | TYSY_HUMAN |
| Accession Number | NP_001062 |
| Immunogen | Human |
| Immunogen Region | 1-313aa |
| Immunogen Sequence |
Additional Info
| Function | Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
| Protein Name | Thymidylate SynthaseTsTsase |
| Database Links | Reactome: R-HSA-499943Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmMitochondrionMitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Protein Names | Thymidylate Synthase proteinTs proteinTsase proteinTYMS proteinTS proteinOK proteinSW-cl.29 protein |
Information sourced from Uniprot.org