Human Thrombopoietin protein (Recombinant) (His-Tag) (STJP019445)

Name: Human Thrombopoietin protein (Recombinant) (His-Tag) (STJP019445)
SKU: STJP019445
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostHEK293 Cells

ImmunogenHuman

STJP019445

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human Thrombopoietin-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE/Bioactivity
Host	HEK293 Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity	Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 range ≤10 ng/ml.

Gene Symbol	THPO
Gene ID	7066
Uniprot ID	TPO_HUMAN
Accession Number	NP_000451.1
Immunogen	Human
Immunogen Region	22-353aa
Immunogen Sequence	SPAPP ACDLRVLSKL LRDSHVLHSR LSQCPEVHPL PTPVLLPAVD FSLGEWKTQM EETKAQDILG AVTLLLEGVM AARGQLGPTC LSSLLGQLSG QVRLLLGALQ SLLGTQLPPQ GRTTAHKDPN AIFLSFQHLL RGKVRFLMLV GGSTLCVRRA PPTTAVPSRT SLVLTLNELP NRTSGLLETN FTASARTTGS GLLKWQQGFR AKIPGLLNQT SRSLDQ

Function	Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Protein Name	Thrombopoietin C-Mpl Ligand Ml Megakaryocyte Colony-Stimulating Factor Megakaryocyte Growth And Development Factor Mgdf Myeloproliferative Leukemia Virus Oncogene Ligand
Database Links	Reactome: R-HSA-76009
Cellular Localisation	Secreted
Alternative Protein Names	Thrombopoietin protein C-Mpl Ligand protein Ml protein Megakaryocyte Colony-Stimulating Factor protein Megakaryocyte Growth And Development Factor protein Mgdf protein Myeloproliferative Leukemia Virus Oncogene Ligand protein THPO protein MGDF protein

Information sourced from Uniprot.org