| Short Description : | Recombinant-Human TGIF2-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | TGIF2 |
| Gene ID: | 60436 |
| Uniprot ID: | TGIF2_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Lys27-Thr92 |
| Post Translational Modifications | The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. |
| Function | Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins. |
| Protein Name | Homeobox Protein Tgif25'-Tg-3'-Interacting Factor 2Tgf-Beta-Induced Transcription Factor 2Tgfb-Induced Factor 2 |
| Database Links | Reactome: R-HSA-2173795Reactome: R-HSA-2173796 |
| Cellular Localisation | NucleusExcluded From Nucleoli |
| Alternative Protein Names | Homeobox Protein Tgif2 protein5'-Tg-3'-Interacting Factor 2 proteinTgf-Beta-Induced Transcription Factor 2 proteinTgfb-Induced Factor 2 proteinTGIF2 protein |
Information sourced from Uniprot.org