Human TGFBI (TGFBI) Antibody Pair (STJAP00921)
General Information
| Short Description | This TGFBI antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R03-8B-6/R02-9Q-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TGFBI |
| Gene ID | 7045 |
| Uniprot ID | BGH3_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Highly expressed in the corneal epithelium. Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.these residues may be required for binding to calcium. According to a more recent report, does not contain vitamin K-dependent gamma-carboxyglutamate residues. The EMI domain contains 2 expected intradomain disulfide bridges (Cys-49-Cys85 and Cys-84-Cys-97) and one unusual interdomain disulfide bridge to the second FAS1 domain (Cys-74-Cys-339). This arrangement violates the predicted disulfide bridge pattern of an EMI domain. |
| Function | Plays a role in cell adhesion. May play a role in cell-collagen interactions. |
| Protein Name | Transforming Growth Factor-Beta-Induced Protein Ig-H3Beta Ig-H3Kerato-EpithelinRgd-Containing Collagen-Associated ProteinRgd-Cap |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixMay Be Associated Both With Microfibrils And With The Cell Surface |
| Alternative Antibody Pair Names | Transforming Growth Factor-Beta-Induced Protein Ig-H3 antibody pairBeta Ig-H3 antibody pairKerato-Epithelin antibody pairRgd-Containing Collagen-Associated Protein antibody pairRgd-Cap antibody pairTGFBI antibody pairBIGH3 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human TGFBI (TGFBI) Antibody Pair (STJAP00921)
This antibody pair detects human TGFBI (Transforming Growth Factor Beta Induced protein, UniProt Q15582). Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated in 0.01M PBS at pH 7.2, and purified by affinity chromatography. Clone IDs are R03-8B-6 and R02-9Q-5 respectively.
This antibody pair has been validated for use in ELISA. The working dilution for each antibody should be determined by the end user for their specific experimental conditions.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C, and avoid repeated freeze/thaw cycles.
Both antibodies were raised in rabbit against a recombinant human TGFBI protein. No immunogen region information is specified for this product.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.