Human TCP1 protein (Recombinant) (His-Tag) (STJP016908)

Name: Human TCP1 protein (Recombinant) (His-Tag) (STJP016908)
SKU: STJP016908
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016908

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Short Description	Recombinant-Human TCP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1mM PMSF, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	TCP1
Gene ID	6950
Uniprot ID	TCPA_HUMAN
Accession Number	NP_110379
Immunogen	Human
Immunogen Region	1-556aa
Immunogen Sequence	MEGPLSVFGD RSTGETIRSQ NVMAAASIAN IVKSSLGPVG LDKMLVDDIG DVTITNDGAT ILKLLEVEHP AAKVLCELAD LQDKEVGDGT TSVVIIAAEL LKNADELVKQ KIHPTSVISG YRLACKEAVR YINENLIVNT DELGRDCLIN AAKTSMSSKI IGINGDFFAN MVVDAVLAIK YTDIRGQPRY PVNSVNILKA HGRSQM

Function	Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.
Protein Name	T-Complex Protein 1 Subunit Alpha Tcp-1-Alpha Cct-Alpha Chaperonin Containing T-Complex Polypeptide 1 Subunit 1
Database Links	Reactome: R-HSA-389957 Reactome: R-HSA-389960 Reactome: R-HSA-390450 Reactome: R-HSA-390471 Reactome: R-HSA-5620922 Reactome: R-HSA-6814122 Reactome: R-HSA-8950505
Cellular Localisation	Cytoplasm Cytosol Cytoskeleton Microtubule Organizing Center Centrosome
Alternative Protein Names	T-Complex Protein 1 Subunit Alpha protein Tcp-1-Alpha protein Cct-Alpha protein Chaperonin Containing T-Complex Polypeptide 1 Subunit 1 protein TCP1 protein CCT1 protein CCTA protein

Information sourced from Uniprot.org