Human TCEA1 protein (Recombinant) (His-Tag) (STJP017645)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017645
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General Information

Short DescriptionRecombinant-Human TCEA1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 7.5) containing 20% Glycerol, 1mM DTT, 50mM NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTCEA1
Gene ID6917
Uniprot IDTCEA1_HUMAN
Accession NumberNP_006747
ImmunogenHuman
Immunogen Region1-301aa
Immunogen SequenceHMEDEVV RFAKKMDKMV QKKNAAGALD LLKELKNIPM TLELLQSTRI GMSVNAIRKQ STDEEVTSLA KSLIKSWKKL LDGPSTEKDL DEKKKEPAIT SQNSPEAREE STSSGNVSNR KDETNARDTY VSSFPRAPST SDSVRLKCRE MLAAALRTGD DYIAIGADEE ELGSQIEEAI YQEIRNTDMK YKNRVRSRIS NLKDAK

Additional Info

Function Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Protein Name Transcription Elongation Factor A Protein 1
Transcription Elongation Factor S-Ii Protein 1
Transcription Elongation Factor Tfiis.o
Database Links Reactome: R-HSA-112382
Reactome: R-HSA-167152
Reactome: R-HSA-167200
Reactome: R-HSA-167238
Reactome: R-HSA-167243
Reactome: R-HSA-167246
Reactome: R-HSA-167287
Reactome: R-HSA-167290
Reactome: R-HSA-674695
Reactome: R-HSA-6781823
Reactome: R-HSA-6781827
Reactome: R-HSA-6782135
Reactome: R-HSA-6782210
Reactome: R-HSA-6796648
Reactome: R-HSA-75955
Cellular Localisation Nucleus
Alternative Protein Names Transcription Elongation Factor A Protein 1 protein
Transcription Elongation Factor S-Ii Protein 1 protein
Transcription Elongation Factor Tfiis.o protein
TCEA1 protein
GTF2S protein
TFIIS protein

Information sourced from Uniprot.org

Citations

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