Human TARC (C-C Motif Chemokine 17) Antibody Pair (STJAP00152)
General Information
| Short Description | This TARC antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL17 |
| Gene ID | 6361 |
| Uniprot ID | CCL17_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human TARC protein.Detection Immunogen: Recombinant Human TARC protein. |
Additional Info
| Function | Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound. |
| Protein Name | C-C Motif Chemokine 17Cc Chemokine TarcSmall-Inducible Cytokine A17Thymus And Activation-Regulated Chemokine |
| Database Links | Reactome: R-HSA-380108 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 17 antibody pairCc Chemokine Tarc antibody pairSmall-Inducible Cytokine A17 antibody pairThymus And Activation-Regulated Chemokine antibody pairCCL17 antibody pairSCYA17 antibody pairTARC antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human TARC (C-C Motif Chemokine 17) Antibody Pair (STJAP00152)
This antibody pair detects human TARC, also known as C-C Motif Chemokine 17 (UniProt Q92583). Reactivity is confirmed for human samples only.
The capture antibody is a mouse monoclonal supplied unconjugated at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol, pH 7.4. The detection antibody is a goat polyclonal supplied biotinylated at 0.5 mg/mL in the same buffer formulation.
This antibody pair is validated for use in ELISA. No other assay formats are specified in the product documentation.
Both the capture and detection antibodies were raised against recombinant human TARC protein. The capture antibody was purified by Protein A or G, while the detection antibody was purified by antigen affinity chromatography.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.