Human SYCP1 protein (Recombinant) (N-His) (STJP015937)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SYCP1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | SYCP1 |
| Gene ID | 6847 |
| Uniprot ID | SYCP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn98-Glu442 |
Additional Info
| Function | Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. |
| Protein Name | Synaptonemal Complex Protein 1Scp-1Cancer/Testis Antigen 8Ct8 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | NucleusChromosomeCentromereIn Tripartite Segments Of Synaptonemal ComplexesBetween Lateral Elements In The NucleusIts N-Terminus Is Found Towards The Center Of The Synaptonemal Complex While The C-Terminus Extends Well Into The Lateral Domain Of The Synaptonemal ComplexOnly Rarely Detected At Centromeres During Leptotene And ZygoteneDetected At Centromeres During Mid-DiploteneWhen It Is No Longer Present Along Chromosome ArmsNo Longer Detected At Centromeres At Later Stages Of Meiosis |
| Alternative Protein Names | Synaptonemal Complex Protein 1 proteinScp-1 proteinCancer/Testis Antigen 8 proteinCt8 proteinSYCP1 proteinSCP1 protein |
Information sourced from Uniprot.org