Human suPAR (Urokinase Plasminogen Activator Surface Receptor) Antibody Pair (STJAP00153)
General Information
| Short Description | This suPAR antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PLAUR |
| Gene ID | 5329 |
| Uniprot ID | UPAR_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human suPAR protein.Detection Immunogen: Recombinant Human suPAR protein. |
Additional Info
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Protein Name | Urokinase Plasminogen Activator Surface ReceptorU-ParUparMonocyte Activation Antigen Mo3Cd Antigen Cd87 |
| Database Links | Reactome: R-HSA-162791Reactome: R-HSA-6798695Reactome: R-HSA-75205 |
| Cellular Localisation | Cell MembraneCell ProjectionInvadopodium MembraneColocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-Integrin- And Vitronectin-Dependent MannerIsoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
| Alternative Antibody Pair Names | Urokinase Plasminogen Activator Surface Receptor antibody pairU-Par antibody pairUpar antibody pairMonocyte Activation Antigen Mo3 antibody pairCd Antigen Cd87 antibody pairPLAUR antibody pairMO3 antibody pairUPAR antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human suPAR (Urokinase Plasminogen Activator Surface Receptor) Antibody Pair (STJAP00153)
This antibody pair is designed to detect human suPAR (Urokinase Plasminogen Activator Surface Receptor), corresponding to UniProt entry Q03405. Reactivity has been confirmed for human samples only.
Both antibodies are polyclonal, raised in goat, and supplied at 0.5 mg/mL. The capture antibody is unconjugated, while the detection antibody is biotin-conjugated. Both are formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair has been validated for use in ELISA. No other assay formats are specified for this product.
Both the capture and detection antibodies were raised against recombinant human suPAR protein. Both antibodies have also been purified by antigen affinity chromatography.
Both components should be stored at -20°C for long-term storage. Repeated freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.