Human SULT1A3 protein (Recombinant) (N-His) (STJP014396)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SULT1A3-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 6% Sucrose, 4% Mannitol, 0.05% Tween 80, pH 8.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | SULT1A3 |
| Gene ID | 445329/6818 |
| Uniprot ID | ST1A3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu295 |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, (R)-adrenaline/epinephrine, (R)-noradrenaline/norepinephrine and serotonin) and phenolic and catechol drugs. Catalyzes the sulfation of T4 (L-thyroxine/3,5,3',5'-tetraiodothyronine), T3 (3,5,3'-triiodothyronine), rT3 (3,3',5'-triiodothyronine) and 3,3'-T2 (3,3'-diiodothyronine), with a substrate preference of 3,3'-T2 > rT3 > T3 > T4. |
| Protein Name | Sulfotransferase 1a3St1a3Aryl Sulfotransferase 1a3/1a4Catecholamine-Sulfating Phenol SulfotransferaseHast3M-PstMonoamine-Sulfating Phenol SulfotransferasePlacental Estrogen SulfotransferaseSulfotransferase 1a3/1a4Sulfotransferase - Monoamine-PreferringThermolabile Phenol SulfotransferaseTl-Pst |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-381038Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Sulfotransferase 1a3 proteinSt1a3 proteinAryl Sulfotransferase 1a3/1a4 proteinCatecholamine-Sulfating Phenol Sulfotransferase proteinHast3 proteinM-Pst proteinMonoamine-Sulfating Phenol Sulfotransferase proteinPlacental Estrogen Sulfotransferase proteinSulfotransferase 1a3/1a4 proteinSulfotransferase - Monoamine-Preferring proteinThermolabile Phenol Sulfotransferase proteinTl-Pst proteinSULT1A3 proteinSTM protein |
Information sourced from Uniprot.org