Human SRP19 protein (Recombinant) (His-Tag) (STJP018223)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human SRP19-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SRP19 |
| Gene ID | 6728 |
| Uniprot ID | SRP19_HUMAN |
| Accession Number | NP_003126 |
| Immunogen | Human |
| Immunogen Region | 1-144aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMACAAAR SPADQDRFIC IYPAYLNNKK TIAEGRRIPI SKAVENPTAT EIQDVCSAVG LNVFLEKNKM YSREWNRDVQ YRGRVRVQLK QEDGSLCLVQ FPSRKSVMLY AAEMIPKLKT RTQKTGGADQ SLQQGEGSKK GKGKKKK |
Additional Info
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex. |
| Protein Name | Signal Recognition Particle 19 Kda ProteinSrp19 |
| Database Links | Reactome: R-HSA-1799339 |
| Cellular Localisation | CytoplasmNucleusNucleolusNucleoplasmAlthough The Signal Recognition Particle Complex Acts In The CytoplasmIt Assembles At Least In Part In The Nucleus And/Or The NucleolusSrp19 Nuclear Import May Be Mediated By Ipo8/Imp8 And Tpno1/Trn |
| Alternative Protein Names | Signal Recognition Particle 19 Kda Protein proteinSrp19 proteinSRP19 protein |
Information sourced from Uniprot.org