Human SORBS1 protein (Recombinant) (N-His) (STJP008963)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SORBS1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SORBS1 |
| Gene ID | 10580 |
| Uniprot ID | SRBS1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr773-Pro929 |
Additional Info
| Post Translational Modifications | O-glycosylated. |
| Function | Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions. |
| Protein Name | Sorbin And Sh3 Domain-Containing Protein 1PonsinSh3 Domain Protein 5Sh3p12C-Cbl-Associated ProteinCap |
| Database Links | Reactome: R-HSA-445355 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembraneCytoplasmCytoskeletonFocal AdhesionNucleusNucleus MatrixColocalizes With The Ten-1 Icd Form Of Tenm1 In The NucleusColocalizes With Actin Stress FibersAlso Detected At The Plasma Membrane And In Neuronal Intranuclear InclusionsColocalized With Pxn At Focal Adhesions During Myogenic Differentiation |
| Alternative Protein Names | Sorbin And Sh3 Domain-Containing Protein 1 proteinPonsin proteinSh3 Domain Protein 5 proteinSh3p12 proteinC-Cbl-Associated Protein proteinCap proteinSORBS1 proteinKIAA0894 proteinKIAA1296 proteinSH3D5 protein |
Information sourced from Uniprot.org