Human SNTA1 protein (Recombinant) (His-Tag) (STJP017485)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human SNTA1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.15M NaCl. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNTA1 |
| Gene ID | 6640 |
| Uniprot ID | SNTA1_HUMAN |
| Accession Number | NP_003089.1 |
| Immunogen | Human |
| Immunogen Region | 1-505aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta. |
| Post Translational Modifications | Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD. |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate. |
| Protein Name | Alpha-1-Syntrophin59 Kda Dystrophin-Associated Protein A1 Acidic Component 1Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1Tacip1Syntrophin-1 |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic SideCell JunctionCytoplasmCytoskeletonIn Skeletal MuscleIt Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions |
| Alternative Protein Names | Alpha-1-Syntrophin protein59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 proteinPro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 proteinTacip1 proteinSyntrophin-1 proteinSNTA1 proteinSNT1 protein |
Information sourced from Uniprot.org