Human SNRPD2 protein (Recombinant) (His-Tag) (STJP017074)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human SNRPD2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 0.2M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNRPD2 |
| Gene ID | 6633 |
| Uniprot ID | SMD2_HUMAN |
| Accession Number | NP_004588.1 |
| Immunogen | Human |
| Immunogen Region | 1-118aa |
| Immunogen Sequence |
Additional Info
| Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. |
| Protein Name | Small Nuclear Ribonucleoprotein Sm D2Sm-D2Snrnp Core Protein D2 |
| Database Links | Reactome: R-HSA-191859Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-9754678 |
| Cellular Localisation | CytoplasmCytosolNucleusSmn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes |
| Alternative Protein Names | Small Nuclear Ribonucleoprotein Sm D2 proteinSm-D2 proteinSnrnp Core Protein D2 proteinSNRPD2 proteinSNRPD1 protein |
Information sourced from Uniprot.org