Human SNRPC protein (Recombinant) (His-Tag) (STJP017447)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human SNRPC-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 0.3M NaCl, 5mM DTT, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNRPC |
| Gene ID | 6631 |
| Uniprot ID | RU1C_HUMAN |
| Accession Number | NP_003084.1 |
| Immunogen | Human |
| Immunogen Region | 1-159aa |
| Immunogen Sequence |
Additional Info
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. |
| Protein Name | U1 Small Nuclear Ribonucleoprotein CU1 Snrnp CU1-CU1c |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | U1 Small Nuclear Ribonucleoprotein C proteinU1 Snrnp C proteinU1-C proteinU1c proteinSNRPC protein |
Information sourced from Uniprot.org