Human SNRNP70 protein (Recombinant) (N-His) (STJP010839)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SNRNP70-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SNRNP70 |
| Gene ID | 6625 |
| Uniprot ID | RU17_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp90-Glu221 |
Additional Info
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. Isoform 3: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. Isoform 4: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. |
| Protein Name | U1 Small Nuclear Ribonucleoprotein 70 KdaU1 Snrnp 70 KdaU1-70kSnrnp70 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus SpeckleNucleusNucleoplasmColocalizes With Scnm1 And Luc7l2 In Nuclear Speckles |
| Alternative Protein Names | U1 Small Nuclear Ribonucleoprotein 70 Kda proteinU1 Snrnp 70 Kda proteinU1-70k proteinSnrnp70 proteinSNRNP70 proteinRNPU1Z proteinRPU1 proteinSNRP70 proteinU1AP1 protein |
Information sourced from Uniprot.org