| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human SLITRK1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | SLITRK1 |
| Gene ID: | 114798 |
| Uniprot ID: | SLIK1_HUMAN |
| Immunogen Region: | Ala16-Ser616 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Undergoes proteolytic cleavage that results in shedding of the ectodomain and cleavage of the C-terminal cytoplasmic tail. Glycosylated. Phosphorylation at Ser-695 is necessary for proper function in promoting neurite outgrowth. |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. |
| Protein Name | Slit And Ntrk-Like Protein 1Leucine-Rich Repeat-Containing Protein 12 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedSynapse |
| Alternative Protein Names | Slit And Ntrk-Like Protein 1 proteinLeucine-Rich Repeat-Containing Protein 12 proteinSLITRK1 proteinKIAA1910 proteinLRRC12 proteinUNQ233 proteinPRO266 protein |
Information sourced from Uniprot.org