Human SLD5/GINS4 protein (Recombinant) (His-Tag) (STJP017900)

Name: Human SLD5/GINS4 protein (Recombinant) (His-Tag) (STJP017900)
SKU: STJP017900
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017900

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Short Description	Recombinant-Human SLD5/GINS4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	GINS4
Gene ID	84296
Uniprot ID	SLD5_HUMAN
Accession Number	NP_115712
Immunogen	Human
Immunogen Region	1-223aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE NILVEPDTDE QRDYVIDLEK GSQHLIRY

Function	Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Protein Name	Dna Replication Complex Gins Protein Sld5 Gins Complex Subunit 4 Cleaved Into - Dna Replication Complex Gins Protein Sld5 - N-Terminally Processed
Database Links	Reactome: R-HSA-176974
Cellular Localisation	Nucleus Chromosome Cytoplasm Associates With Chromatin
Alternative Protein Names	Dna Replication Complex Gins Protein Sld5 protein Gins Complex Subunit 4 Cleaved Into - Dna Replication Complex Gins Protein Sld5 - N-Terminally Processed protein GINS4 protein SLD5 protein

Information sourced from Uniprot.org