Human SLC30A10 protein (Recombinant) (N-His) (STJP016049)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SLC30A10-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | SLC30A10 |
| Gene ID | 55532 |
| Uniprot ID | ZNT10_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys300-Gly427 |
Additional Info
| Function | Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange. Required for intracellular manganese homeostasis, an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Manganese can also be cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Could also have an intracellular zinc ion transporter activity, directly regulating intracellular zinc ion homeostasis and more indirectly various signaling pathway and biological processes. |
| Protein Name | Calcium/Manganese Antiporter Slc30a10Solute Carrier Family 30 Member 10Zinc Transporter 10Znt-10 |
| Database Links | Reactome: R-HSA-425410 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneRecycling Endosome MembraneEarly Endosome MembraneLocalization To The Golgi And Plasma Membrane Is Regulated By Zinc |
| Alternative Protein Names | Calcium/Manganese Antiporter Slc30a10 proteinSolute Carrier Family 30 Member 10 proteinZinc Transporter 10 proteinZnt-10 proteinSLC30A10 proteinZNT10 proteinZNT8 protein |
Information sourced from Uniprot.org