Human SLC29A1 protein (Recombinant) (N-His) (STJP016083)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SLC29A1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | SLC29A1 |
| Gene ID | 2030 |
| Uniprot ID | S29A1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn30-Asn82&Arg228-Val291 |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure. |
| Protein Name | Equilibrative Nucleoside Transporter 1Hent1Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside TransporterEquilibrative Nbmpr-Sensitive Nucleoside TransporterEs Nucleoside TransporterNucleoside Transporter - Es-TypeSolute Carrier Family 29 Member 1 |
| Database Links | Reactome: R-HSA-83936Reactome: R-HSA-9748787Reactome: R-HSA-9755088 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneCell MembraneLocalized To The Basolateral Membrane Of Sertoli CellsLocalized To The Cell Membrane Of Erythrocytes |
| Alternative Protein Names | Equilibrative Nucleoside Transporter 1 proteinHent1 proteinEquilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter proteinEquilibrative Nbmpr-Sensitive Nucleoside Transporter proteinEs Nucleoside Transporter proteinNucleoside Transporter - Es-Type proteinSolute Carrier Family 29 Member 1 proteinSLC29A1 proteinENT1 protein |
Information sourced from Uniprot.org